How to find studies and lead variants assigned by V2G

This example illustrates how you can find all studies from the GWAS Catalog or UK Biobank e.g. GCST008413 and NEALE2_1687, plus all lead variants assigned to your gene of interest (ENSG00000158158) as a result of the V2G pipeline.

Use the studiesAndLeadVariantsForGenequery:

{
studiesAndLeadVariantsForGene(geneId: "ENSG00000158158") {
indexVariant {
id
rsId
}
study {
studyId
traitReported
}
}
}

Response

{
"data": {
"studiesAndLeadVariantsForGene": [
{
"indexVariant": {
"id": "2_96663115_C_T",
"rsId": "rs17634791"
},
"study": {
"studyId": "NEALE2_30180_raw",
"traitReported": "Lymphocyte percentage"
}
},
{
"indexVariant": {
"id": "2_96506388_G_A",
"rsId": "rs1866444"
},
"study": {
"studyId": "GCST008413",
"traitReported": "Core binding factor acute myeloid leukemia"
}
},
{
"indexVariant": {
"id": "2_96535945_G_A",
"rsId": "rs2579500"
},
"study": {
"studyId": "NEALE2_30210_raw",
"traitReported": "Eosinophill percentage"
}
},
{
"indexVariant": {
"id": "2_96535945_G_A",
"rsId": "rs2579500"
},
"study": {
"studyId": "GCST004606",
"traitReported": "Eosinophil counts"
}
},
{
"indexVariant": {
"id": "2_96297946_A_G",
"rsId": "rs772178"
},
"study": {
"studyId": "GCST006258",
"traitReported": "Diastolic blood pressure"
}
},
{
"indexVariant": {
"id": "2_96388214_TTAGA_T",
"rsId": "rs35205062"
},
"study": {
"studyId": "NEALE2_30150",
"traitReported": "Eosinophill count"
}
},
{
"indexVariant": {
"id": "2_96189503_G_A",
"rsId": "rs4907230"
},
"study": {
"studyId": "NEALE2_30190_raw",
"traitReported": "Monocyte percentage"
}
},
{
"indexVariant": {
"id": "2_96535945_G_A",
"rsId": "rs2579500"
},
"study": {
"studyId": "GCST007065",
"traitReported": "Eosinophil counts"
}
},
{
"indexVariant": {
"id": "2_96535945_G_A",
"rsId": "rs2579500"
},
"study": {
"studyId": "GCST004624",
"traitReported": "Sum eosinophil basophil counts"
}
},
{
"indexVariant": {
"id": "2_96510897_C_T",
"rsId": "rs2579503"
},
"study": {
"studyId": "GCST007269",
"traitReported": "Pulse pressure"
}
},
{
"indexVariant": {
"id": "2_96535945_G_A",
"rsId": "rs2579500"
},
"study": {
"studyId": "GCST004600",
"traitReported": "Eosinophil percentage of white cells"
}
},
{
"indexVariant": {
"id": "2_96381261_G_A",
"rsId": "rs1081707"
},
"study": {
"studyId": "GCST007268",
"traitReported": "Diastolic blood pressure"
}
},
{
"indexVariant": {
"id": "2_96564337_G_A",
"rsId": "rs2708977"
},
"study": {
"studyId": "GCST004617",
"traitReported": "Eosinophil percentage of granulocytes"
}
},
{
"indexVariant": {
"id": "2_96479597_T_TTG",
"rsId": "rs113359549"
},
"study": {
"studyId": "GCST004606",
"traitReported": "Eosinophil counts"
}
},
{
"indexVariant": {
"id": "2_96564337_G_A",
"rsId": "rs2708977"
},
"study": {
"studyId": "GCST004623",
"traitReported": "Neutrophil percentage of granulocytes"
}
},
{
"indexVariant": {
"id": "2_96502225_T_C",
"rsId": "rs2579505"
},
"study": {
"studyId": "NEALE2_30150",
"traitReported": "Eosinophill count"
}
},
{
"indexVariant": {
"id": "2_96116247_G_C",
"rsId": "rs3111873"
},
"study": {
"studyId": "NEALE2_4079_raw",
"traitReported": "Diastolic blood pressure, automated reading"
}
},
{
"indexVariant": {
"id": "2_95936694_T_C",
"rsId": null
},
"study": {
"studyId": "GCST004617",
"traitReported": "Eosinophil percentage of granulocytes"
}
},
{
"indexVariant": {
"id": "2_96009418_T_C",
"rsId": "rs2579519"
},
"study": {
"studyId": "GCST004280",
"traitReported": "Diastolic blood pressure"
}
},
{
"indexVariant": {
"id": "2_96093689_T_C",
"rsId": "rs2579547"
},
"study": {
"studyId": "GCST004609",
"traitReported": "Monocyte percentage of white cells"
}
},
{
"indexVariant": {
"id": "2_96377542_G_GT",
"rsId": "rs561539268"
},
"study": {
"studyId": "NEALE2_1687",
"traitReported": "Comparative body size at age 10"
}
},
{
"indexVariant": {
"id": "2_96259531_T_A",
"rsId": "rs4907307"
},
"study": {
"studyId": "GCST006568",
"traitReported": "Highest math class taken (MTAG) [MTAG]"
}
},
{
"indexVariant": {
"id": "2_96739703_G_A",
"rsId": "rs2271893"
},
"study": {
"studyId": "GCST001358",
"traitReported": "Bipolar disorder"
}
},
{
"indexVariant": {
"id": "2_96714492_T_G",
"rsId": "rs56361249"
},
"study": {
"studyId": "GCST003962",
"traitReported": "Bipolar disorder"
}
},
{
"indexVariant": {
"id": "2_96710670_A_AT",
"rsId": "rs57195239"
},
"study": {
"studyId": "GCST008103",
"traitReported": "Bipolar disorder"
}
},
{
"indexVariant": {
"id": "2_96739703_G_A",
"rsId": "rs2271893"
},
"study": {
"studyId": "GCST006585_941",
"traitReported": "Blood protein levels [LMAN2L]"
}
},
{
"indexVariant": {
"id": "2_96686103_A_G",
"rsId": "rs7599598"
},
"study": {
"studyId": "GCST006193_3",
"traitReported": "Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) [EA]"
}
},
{
"indexVariant": {
"id": "2_96686103_A_G",
"rsId": "rs7599598"
},
"study": {
"studyId": "GCST006166_6",
"traitReported": "Diastolic blood pressure x alcohol consumption interaction (2df test) [Asian, EA]"
}
},
{
"indexVariant": {
"id": "2_96686103_A_G",
"rsId": "rs7599598"
},
"study": {
"studyId": "GCST006190",
"traitReported": "Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)"
}
},
{
"indexVariant": {
"id": "2_96686103_A_G",
"rsId": "rs7599598"
},
"study": {
"studyId": "GCST006166_8",
"traitReported": "Diastolic blood pressure x alcohol consumption interaction (2df test) [EA]"
}
},
{
"indexVariant": {
"id": "2_96686103_A_G",
"rsId": "rs7599598"
},
"study": {
"studyId": "GCST006193",
"traitReported": "Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test)"
}
},
{
"indexVariant": {
"id": "2_96686103_A_G",
"rsId": "rs7599598"
},
"study": {
"studyId": "GCST006190_3",
"traitReported": "Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) [EA]"
}
},
{
"indexVariant": {
"id": "2_96752905_T_G",
"rsId": "rs189255944"
},
"study": {
"studyId": "NEALE2_20151_raw",
"traitReported": "Forced vital capacity (fvc), best measure"
}
},
{
"indexVariant": {
"id": "2_96617939_T_C",
"rsId": "rs183743021"
},
"study": {
"studyId": "NEALE2_20015_raw",
"traitReported": "Sitting height"
}
},
{
"indexVariant": {
"id": "2_97716827_T_C",
"rsId": "rs11683207"
},
"study": {
"studyId": "SAIGE_401_1",
"traitReported": "Essential hypertension"
}
},
{
"indexVariant": {
"id": "2_97716827_T_C",
"rsId": "rs11683207"
},
"study": {
"studyId": "SAIGE_401",
"traitReported": "Hypertension"
}
},
{
"indexVariant": {
"id": "2_97131943_T_C",
"rsId": "rs13390019"
},
"study": {
"studyId": "GCST008757",
"traitReported": "Alcohol consumption"
}
},
{
"indexVariant": {
"id": "2_96941334_A_G",
"rsId": "rs6728642"
},
"study": {
"studyId": "GCST005081",
"traitReported": "Bipolar disorder lithium response (continuous) or schizophrenia"
}
},
{
"indexVariant": {
"id": "2_96062159_C_T",
"rsId": "rs17119859"
},
"study": {
"studyId": "GCST004623",
"traitReported": "Neutrophil percentage of granulocytes"
}
},
{
"indexVariant": {
"id": "2_95991827_A_G",
"rsId": "rs62155511"
},
"study": {
"studyId": "GCST007269",
"traitReported": "Pulse pressure"
}
},
{
"indexVariant": {
"id": "2_97658891_G_A",
"rsId": "rs11692435"
},
"study": {
"studyId": "GCST007328",
"traitReported": "Alcohol consumption (drinks per week)"
}
},
{
"indexVariant": {
"id": "2_97658891_G_A",
"rsId": "rs11692435"
},
"study": {
"studyId": "GCST007474",
"traitReported": "Smoking initiation (ever regular vs never regular)"
}
},
{
"indexVariant": {
"id": "2_97658891_G_A",
"rsId": "rs11692435"
},
"study": {
"studyId": "GCST007992",
"traitReported": "Colorectal cancer"
}
},
{
"indexVariant": {
"id": "2_97658891_G_A",
"rsId": "rs11692435"
},
"study": {
"studyId": "GCST007039",
"traitReported": "Body mass index"
}
},
{
"indexVariant": {
"id": "2_97658891_G_A",
"rsId": "rs11692435"
},
"study": {
"studyId": "GCST007468",
"traitReported": "Smoking initiation (ever regular vs never regular) (MTAG)"
}
},
{
"indexVariant": {
"id": "2_99329966_C_CA",
"rsId": "rs70940164"
},
"study": {
"studyId": "NEALE2_23115_raw",
"traitReported": "Leg fat percentage (left)"
}
},
{
"indexVariant": {
"id": "2_97658891_G_A",
"rsId": "rs11692435"
},
"study": {
"studyId": "GCST007461",
"traitReported": "Alcohol consumption (drinks per week)"
}
},
{
"indexVariant": {
"id": "2_97658891_G_A",
"rsId": "rs11692435"
},
"study": {
"studyId": "GCST007472",
"traitReported": "Alcohol consumption (drinks per week) (MTAG)"
}
},
{
"indexVariant": {
"id": "2_97658891_G_A",
"rsId": "rs11692435"
},
"study": {
"studyId": "GCST008522",
"traitReported": "Bitter alcoholic beverage consumption"
}
},
{
"indexVariant": {
"id": "2_96617939_T_C",
"rsId": "rs183743021"
},
"study": {
"studyId": "NEALE2_3062_raw",
"traitReported": "Forced vital capacity (fvc)"
}
},
{
"indexVariant": {
"id": "2_96617939_T_C",
"rsId": "rs183743021"
},
"study": {
"studyId": "NEALE2_20153_raw",
"traitReported": "Forced expiratory volume in 1-second (fev1), predicted"
}
},
{
"indexVariant": {
"id": "2_97973620_T_A",
"rsId": "rs905484"
},
"study": {
"studyId": "NEALE2_30210_raw",
"traitReported": "Eosinophill percentage"
}
},
{
"indexVariant": {
"id": "2_97718216_C_T",
"rsId": "rs11687510"
},
"study": {
"studyId": "GCST008413",
"traitReported": "Core binding factor acute myeloid leukemia"
}
},
{
"indexVariant": {
"id": "2_97740700_T_C",
"rsId": "rs4851462"
},
"study": {
"studyId": "GCST006630",
"traitReported": "Diastolic blood pressure"
}
},
{
"indexVariant": {
"id": "2_97774654_G_A",
"rsId": "rs10191483"
},
"study": {
"studyId": "NEALE2_30200_raw",
"traitReported": "Neutrophill percentage"
}
},
{
"indexVariant": {
"id": "2_97921970_A_G",
"rsId": "rs1578957"
},
"study": {
"studyId": "GCST006287",
"traitReported": "Adolescent idiopathic scoliosis"
}
},
{
"indexVariant": {
"id": "2_95848679_C_T",
"rsId": "rs13406335"
},
"study": {
"studyId": "NEALE2_30210_raw",
"traitReported": "Eosinophill percentage"
}
},
{
"indexVariant": {
"id": "2_97032743_A_C",
"rsId": "rs13005320"
},
"study": {
"studyId": "NEALE2_30150",
"traitReported": "Eosinophill count"
}
},
{
"indexVariant": {
"id": "2_94695807_T_A",
"rsId": "rs191977771"
},
"study": {
"studyId": "NEALE2_50_raw",
"traitReported": "Standing height"
}
},
{
"indexVariant": {
"id": "2_94717678_C_T",
"rsId": "rs114519920"
},
"study": {
"studyId": "NEALE2_1697",
"traitReported": "Comparative height size at age 10"
}
},
{
"indexVariant": {
"id": "2_96752905_T_G",
"rsId": "rs189255944"
},
"study": {
"studyId": "NEALE2_50_raw",
"traitReported": "Standing height"
}
},
{
"indexVariant": {
"id": "2_96835038_A_G",
"rsId": "rs78381888"
},
"study": {
"studyId": "GCST006568",
"traitReported": "Highest math class taken (MTAG) [MTAG]"
}
},
{
"indexVariant": {
"id": "2_96835038_A_G",
"rsId": "rs78381888"
},
"study": {
"studyId": "GCST006573",
"traitReported": "Self-reported math ability"
}
},
{
"indexVariant": {
"id": "2_96835038_A_G",
"rsId": "rs78381888"
},
"study": {
"studyId": "GCST006569",
"traitReported": "Self-reported math ability (MTAG) [MTAG]"
}
},
{
"indexVariant": {
"id": "2_96858148_G_A",
"rsId": "rs79460537"
},
"study": {
"studyId": "GCST008839",
"traitReported": "Height"
}
},
{
"indexVariant": {
"id": "2_96900314_C_T",
"rsId": "rs114707893"
},
"study": {
"studyId": "NEALE2_1697",
"traitReported": "Comparative height size at age 10"
}
},
{
"indexVariant": {
"id": "2_96916498_A_T",
"rsId": "rs13018621"
},
"study": {
"studyId": "NEALE2_6138_1",
"traitReported": "College or university degree | qualifications"
}
},
{
"indexVariant": {
"id": "2_96989603_A_G",
"rsId": "rs148947061"
},
"study": {
"studyId": "NEALE2_5375_raw",
"traitReported": "Longest period of unenthusiasm / disinterest"
}
}
]
}
}
Finding studies and lead variants assigned by V2G using the GraphiQL browser

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