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Future Plans

There are some of the new functionalities and data coming up in future releases of Open Targets Genetics:
  • Tissue/SNP enrichment across diseases and traits (CHEERS method)
  • Mendelian Randomisation (6 proteomic summary stat data)
  • Tissue/trait-specific ‘Locus to Gene’ score
  • Therapeutic-area specific profiles (e.g. only include functional data relevant to immune-related disease in variant-to-gene assignment/scoring)
  • PheWAS based on rare variants
In the meantime, the team is working on refactoring Open Targets Genetics pipelines, aiming to:
  • Re-focusing the product around Target ID
  • Creating a gold standard toolkit for post-GWAS analysis
  • Faster/robust addition of new datasets and datatypes
  • Reducing computational and financial cost
Please see this repository for more information.
To be informed of future updates, follow Open Targets on Twitter and LinkedIn, and keep an eye on the Open Targets Blog and Open Targets Community.
Last modified 4mo ago